Clues to why most survived China melamine scandal

WASHINGTON (AP) — Scientists wondering why some children and not others survived one of China's worst food safety scandals have uncovered a suspect: germs that live in the gut.

In 2008, at least six babies died and 300,000 became sick after being fed infant formula that had been deliberately and illegally tainted with the industrial chemical melamine. There were some lingering puzzles: How did it cause kidney failure, and why wasn't everyone equally at risk?

A team of researchers from the U.S. and China re-examined those questions in a series of studies in rats. In findings released Wednesday, they reported that certain intestinal bacteria play a crucial role in how the body handles melamine.

The intestines of all mammals teem with different species of bacteria that perform different jobs. To see if one of those activities involves processing melamine, researchers from the University of North Carolina at Greensboro and Shanghai Jiao Tong University gave lab rats antibiotics to kill off some of the germs — and then fed them melamine.

The antibiotic-treated rats excreted twice as much of the melamine as rats that didn't get antibiotics, and they experienced fewer kidney stones and other damage.

A closer look identified why: A particular intestinal germ — named Klebsiella terrigena — was metabolizing melamine to create a more toxic byproduct, the team reported in the journal Science Translational Medicine.

Previous studies have estimated that fewer than 1 percent of healthy people harbor that bacteria species. A similar fraction of melamine-exposed children in China got sick, the researchers wrote. But proving that link would require studying stool samples preserved from affected children, they cautioned.

Still, the research is pretty strong, said microbiologist Jack Gilbert of the University of Chicago and Argonne National Laboratory, who wasn't involved in the new study.

More importantly, "this paper adds to a growing body of evidence which suggests that microbes in the body play a significant role in our response to toxicity and in our health in general," Gilbert said.

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Dorner Not IDed, But Manhunt Considered Over

Though they have not yet identified burned remains found at the scene of Tuesday's fiery, armed standoff, San Bernardino, Calif., officials consider the manhunt over for Christopher Dorner, the fugitive ex-cop accused of going on a killing spree.

"The events that occurred yesterday in the Big Bear area brought to close an extensive manhunt," San Bernardino County Sheriff John McMahon told reporters this evening.

"I cannot absolutely, positively confirm it was him," he added.

However, he noted the physical description of the suspect authorities pursued to a cabin at the standoff scene, as well as the suspect's behavior during the chase and standoff, matched Dorner, 33.

The charred remains of the body believed to be Dorner were removed from the cabin high in the San Bernardino Mountains near Big Bear, Calif., the apparent site of Dorner's last stand. Cornered inside the mountain cabin Tuesday, the suspect shot at cops, killing one deputy and wounding another, before the building was consumed by flames.

"We did not intentionally burn down that cabin to get Mr. Dorner out," McMahon said tonight, though he noted pyrotechnic canisters known as "burners" were fired into the cabin during a tear gas assault in an effort to flush out Dorner. The canisters generate high temperatures, he added.

The deputies wounded in the firefight were airlifted to a nearby hospital, where one died, police said.

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Christopher Dorner Manhunt: Inside the Shootout Watch Video

The deceased deputy was identified tonight as Det. Jeremiah MacKay, 35, a 15-year veteran and the father of two children -- a daughter, 7, and son, 4 months old.

"Our department is grieving from this event," McMahon said. "It is a terrible deal for all of us."

The Associated Press quoted MacKay on the Dorner dragnet Tuesday, noting that he had been on patrol since 5 a.m. Saturday.

"This one you just never know if the guy's going to pop out, or where he's going to pop out," MacKay said. "We're hoping this comes to a close without more casualties. The best thing would be for him to give up."

The wounded deputy, identified as Alex Collins, was undergoing multiple surgeries for his wounds at a hospital, McMahon said, but was expected to make a full recovery.

Before the final standoff, Dorner was apparently holed up in a snow-covered cabin in the California mountains just steps from where police had set up a command post and held press conferences during a five-day manhunt.

The manhunt for Dorner, one of the biggest in recent memory, led police to follow clues across the West and into Mexico, but it ended just miles from where Dorner's trail went cold last week.

Residents of the area were relieved today that after a week of heightened police presence and fear that Dorner was likely dead.

"I'm glad no one else can get hurt and they caught him. I'm happy they caught the bad guy," said Ashley King, a waitress in the nearby town of Angelus Oaks, Calif.

Hundreds of cops scoured the mountains near Big Bear, a resort area in Southern California, since last Thursday using bloodhounds and thermal-imaging technology mounted to helicopters, in the search for Dorner. The former police officer and Navy marksman was suspected to be the person who killed a cop and cop's daughter and issued a "manifesto" declaring he was bent on revenge and pledging to kill dozens of LAPD cops and their family members.

But it now appears that Dorner never left the area, and may have hid out in an unoccupied cabin just steps from where cops had set up a command center.

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North Korean nuclear test draws anger, including from China

SEOUL (Reuters) - North Korea conducted its third nuclear test on Tuesday in defiance of U.N. resolutions, drawing condemnation from around the world, including from its only major ally, China, which summoned the North Korean ambassador to protest.

Pyongyang said the test was an act of self-defense against "U.S. hostility" and threatened stronger steps if necessary.

The test puts pressure on U.S. President Barack Obama on the day of his State of the Union speech and also puts China in a tight spot, since it comes in defiance of Beijing's admonishments to North Korea to avoid escalating tensions.

The U.N. Security Council held an emergency meeting at which its members, including China, "strongly condemned" the test and vowed to start work on appropriate measures in response, the president of the council said.

North Korean leader Kim Jong-un, the third of his line to rule the country, has presided over two long-range rocket launches and a nuclear test during his first year in power, pursuing policies that have propelled his impoverished and malnourished country closer to becoming a nuclear weapons power.

North Korea said the test had "greater explosive force" than those it conducted in 2006 and 2009. Its KCNA news agency said it had used a "miniaturized" and lighter nuclear device, indicating it had again used plutonium, which is suitable for use as a missile warhead.

China, which has shown signs of increasing exasperation with the recent bellicose tone of its reclusive neighbor, summoned the North Korean ambassador in Beijing and protested sternly, the Foreign Ministry said.

Foreign Minister Yang Jiechi said China was "strongly dissatisfied and resolutely opposed" to the test and urged North Korea to "stop any rhetoric or acts that could worsen situations and return to the right course of dialogue and consultation as soon as possible".

Analysts said the test was a major embarrassment to China, which is a permanent member of the Security Council and North Korea's sole major economic and diplomatic ally.

Obama called the test a "highly provocative act" that hurt regional stability.

"The danger posed by North Korea's threatening activities warrants further swift and credible action by the international community. The United States will also continue to take steps necessary to defend ourselves and our allies," Obama said.

U.S. Ambassador to the United Nations Susan Rice said Washington and its allies intended to "augment the sanctions regime" already in place due to Pyongyang's previous atomic tests. North Korea is already one of the most heavily sanctioned states in the world and has few external economic links that can be targeted.

Japanese Prime Minister Shinzo Abe said the test was a "grave threat" that could not be tolerated.

Russian Foreign Minister Sergei Lavrov urged North Korea to abandon its nuclear arms program and return to talks. NATO condemned the test as an "irresponsible act."

South Korea, still technically at war with North Korea after a 1950-53 civil war ended in a mere truce, also denounced the test. Obama spoke to South Korean President Lee Myung-bak on Tuesday and told him the United States "remains steadfast in its defense commitments" to Korea, the White House said.

MAXIMUM RESTRAINT

North Korea's Foreign Ministry said the test was "only the first response we took with maximum restraint".

"If the United States continues to come out with hostility and complicates the situation, we will be forced to take stronger, second and third responses in consecutive steps," it said in a statement carried by the official KCNA news agency.

North Korea - which gave the U.S. State Department advance warning of the test - often threatens the United States and its "puppet", South Korea, with destruction in colorful terms.

North Korea told the U.N. disarmament forum in Geneva that it would never bow to resolutions on its nuclear program and that prospects were "gloomy" for the denuclearization of the divided Korean peninsula because of a "hostile" U.S. policy.

Suzanne DiMaggio, an analyst at the Asia Society in New York, said North Korea had embarrassed China with the test. "China's inability to dissuade North Korea from carrying through with this third nuclear test reveals Beijing's limited influence over Pyongyang's actions in unusually stark terms," she said.

Mark Fitzpatrick of the International Institute for Strategic Studies think tank, said: "The test is hugely insulting to China, which now can be expected to follow through with threats to impose sanctions."

The magnitude of the explosion was roughly twice that of the 2009 test, according to the Vienna-based Comprehensive Nuclear-Test Ban Treaty Organization. The U.S. Geological Survey said that a seismic event measuring 5.1 magnitude had occurred.

U.S. intelligence agencies were analyzing the event and found that North Korea probably conducted an underground nuclear explosion with a yield of "approximately several kilotons", the Office of the Director of National Intelligence said.

Nuclear experts have described Pyongyang's previous two tests as puny by international standards. The yield of the 2006 test has been estimated at less than 1 kiloton (1,000 tons of TNT equivalent) and the second at some 2-7 kilotons, compared with 20 kilotons for a Nagasaki-type bomb.

Initial indications are that the test involved the latest version of a plutonium-based prototype weapon, according to one current and one former U.S. national security official. Both previous tests involved plutonium. If it turns out the test was of a new uranium-based weapon, it would show that North Korea has made more progress on uranium enrichment than previously thought.

The United States uses WC-135 Constant Phoenix "sniffer" aircraft to collect samples to identify nuclear explosions. These would need to be deployed quickly to detect whether highly enriched uranium rather than plutonium was used because uranium decays to undetectable levels within a matter of days. Plutonium takes much longer to decay.

North Korea trumpeted news of the test on its state television channel to patriotic music against a backdrop of its national flag.

"It was confirmed that the nuclear test that was carried out at a high level in a safe and perfect manner using a miniaturized and lighter nuclear device with greater explosive force than previously did not pose any negative impact on the surrounding ecological environment," KCNA said.

North Korea linked the test to its technical prowess in launching a long-range rocket in December, a move that triggered the U.N. sanctions, backed by China, that Pyongyang said prompted it to take Tuesday's action.

The North's ultimate aim, Washington believes, is to design an intercontinental ballistic missile capable of carrying a nuclear warhead that could hit the United States. North Korea says the program is aimed at putting satellites in space.

Despite its three nuclear tests and long-range rocket tests, North Korea is not believed to be close to manufacturing a nuclear missile capable of hitting the United States.

It used plutonium in previous nuclear tests and before Tuesday there had been speculation that it would use highly enriched uranium so as to conserve its plutonium stocks, as testing eats into its limited supply of materials to construct a nuclear bomb.

"VICIOUS CYCLE"

When Kim Jong-un, who is 30, took power after his father's death in December 2011, there were hopes that he would bring reforms and end Kim Jong-il's "military first" policies.

Instead, North Korea, whose economy is smaller than it was 20 years ago and where a third of children are believed to be malnourished, appears to be trapped in a cycle of sanctions followed by further provocations.

"The more North Korea shoots missiles, launches satellites or conducts nuclear tests, the more the U.N. Security Council will impose new and more severe sanctions," said Shen Dingli, a professor at Shanghai's Fudan University. "It is an endless, vicious cycle."

Options for the international community appear to be in short supply. Diplomats at the United Nations said negotiations on new sanctions could take weeks since China is likely to resist tough new measures for fear they could lead to further retaliation by the North Korean leadership.

Beijing has also been concerned that tougher sanctions could further weaken North Korea's economy and prompt a flood of refugees into China.

Tuesday's action appeared to have been timed for the run-up to February 16 anniversary celebrations of Kim Jong-il's birthday, as well as to achieve maximum international attention.

Significantly, the test comes at a time of political transition in China, Japan and South Korea, and as Obama begins his second term. The U.S. president will likely have to tweak his State of the Union address due to be given on Tuesday.

Japanese Prime Minister Shinzo Abe is bedding down a new government and South Korea's new president, Park Geun-hye, is preparing to take office on February 25.

China too is in the midst of a once-in-a-decade leadership transition to Xi Jinping, who takes office in March. Both Abe and Xi are staunch nationalists.

The longer-term game plan from Pyongyang may be to restart international talks aimed at winning food and financial aid. China urged it to return to the stalled "six-party" talks on its nuclear program, hosted by China and including the two Koreas, the United States, Japan and Russia.

Its puny economy and small diplomatic reach mean that North Korea struggles to win attention on the global stage - other than through nuclear tests and attacks on South Korea, the last of which was made in 2010.

"Now the next step for North Korea will be to offer talks... - any form to start up discussion again to bring things to their advantage," predicted Jeung Young-tae, senior research fellow at the Korea Institute for National Unification in Seoul.

(Additional reporting by Jack Kim, Christine Kim and Jumin Park in SEOUL; Linda Sieg in TOKYO; Louis Charbonneau and Michelle Nichols at the UNITED NATIONS; Fredrik Dahl in VIENNA; Michael Martina and Chen Aizhu in BEIJING; Mette Fraende in COPENHAGEN; Adrian Croft, Charlie Dunmore and Justyna Pawlak in BRUSSELS; Mark Hosenball, Paul Eckert, Roberta Rampton, Tabassum Zakaria and Jeff Mason in WASHINGTON; Editing by Nick Macfie, Claudia Parsons and David Brunnstrom)

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Japan 'shocked' by IOC wrestling decision

TOKYO: Wrestling power Japan, which swept four gold in London, reacted with dismay Wednesday after Olympic chiefs said the 2020 Games would not include the sport, depriving the country of a rich source of medals.

"I really don't know why. I am so devastated that I don't know what to do," said Saori Yoshida, Japan's undisputed wrestling queen who has won a record 13 straight Olympic and world championship gold medals over 10 years.

Yoshida, a 55kg-class freestyle wrestler who last year received the government's "People's Honour Award" for her achievements, is the face of Tokyo's campaign for the right to host the 2020 Games.

The decision to drop wrestling, taken by the 15 members of the International Olympic Committee (IOC) executive board, has yet to be ratified by all members of the body, but leaves the sport fighting with seven other disciplines for the vacant spot in seven years' time.

Japan Wrestling Federation chairman Tomiaki Fukuda expressed his frustration at the decision.

"I am really shocked. I have no idea why they decided this," Fukuda said in an interview with TV Asahi.

He has also said on the federation's website: "I am dissatisfied and baffled. I want to know the reasons why the IOC removed wrestling."

Local media dubbed the IOC decision a "crisis for Japan's strong suit".

Chief Cabinet Secretary Yoshihide Suga also expressed disappointment at the IOC vote.

"Wrestling is one of Japan's strongest sports," he said. "It is said to be the oldest sport in the world... The decision is very disappointing."

This is the latest blow to Japanese sport after the national women's judo coach resigned in disgrace after admitting he had physically beaten his athletes as he tried to discipline them.

That scandal came just weeks after a schoolboy killed himself after repeatedly being subjected to violence by his basketball coach.

-AFP/gn

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Battle lines drawn up in Tripura

AGARTALA: Battle lines have been drawn up for Thursday's polls to the 60-member Tripura assembly where heavyweights chief minister Manik Sarkar, TPCC president Sudip Ray Barman and president of Indigenous Nationalist Party of Tripura Bijay Hrankhwal are among 249 candidates in the fray.

The Left Front is hoping to script history by returning to power for a fifth consecutive time.

The main contest will be between the Left Front and its allies and the Congress and its partners.

The CPM, the dominant partner in the Left Front, is contesting 56 seats, RSP two and CPI and Forward Block one each.

The Congress is contesting 48 seats and its alliance partners INPT in 11 and National Conference of Tripura in one.

The candidates include 14 women, who are four less than those who had contested in the 2008 elections.

An electorate of 23,52,505 including 11,64,656 women are expected to exercise their franchise in the election contested by a total of 16 political parties and independents.

The CPM, which has taken credit for ending the four-decade-old insurgency in the state and ensuring peace and communal harmony, is projecting Tripura as a model state in terms of good governance having topped the list in the implementation of MNREGA.

The CPM has also highlighted the 15 awards it received from the Centre for successful implementation of various schemes.

The Congress-INPT-NCT alliance has made "bad governance" of the Manik Sarkar-led government a poll issue, alleging that despite availability of central funds, employees, unemployed and farmers remained deprived during the 20-year LF regime.

Corruption and nepotism by party leaders and partisan behaviour of the government are also important issues for the alliance.

Prominent leaders who campaigned in the run-up to the election include Congress Vice-President Rahul Gandhi, Union minister Deepa Das Munshi, Arunachal Pradesh Chief Minister Nabam Tuki, Union finance minister P Chidambaram, CPM leaders Prakash Karat, Sitaram Yechury, Surya Kanta Mishra and Brinda Karat.

Of the 3,041 booths, 409 have been identified as very sensitive (A+), 535 booths as very sensitive (A) and 726 booths as sensitive.

Altogether 250 companies of central paramilitary forces have been deployed in the state to maintain law and order.

The Border Security Force has sealed the 856 km border with Bangladesh and deployed additional forces to prevent infiltration.

The Election Commission has formed flying squads and Static Surveillance Teams to combat the menace of cash doles and bribes and carrying of illegal arms.

Static Surveillance Teams and Flying squads have been set up in all 60 constituencies with police and government officials headed by a magistrate.

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Study questions kidney cancer treatment in elderly

In a stunning example of when treatment might be worse than the disease, a large review of Medicare records finds that older people with small kidney tumors were much less likely to die over the next five years if doctors monitored them instead of operating right away.

Even though nearly all of these tumors turned out to be cancer, they rarely proved fatal. And surgery roughly doubled patients' risk of developing heart problems or dying of other causes, doctors found.

After five years, 24 percent of those who had surgery had died, compared to only 13 percent of those who chose monitoring. Just 3 percent of people in each group died of kidney cancer.

The study only involved people 66 and older, but half of all kidney cancers occur in this age group. Younger people with longer life expectancies should still be offered surgery, doctors stressed.

The study also was observational — not an experiment where some people were given surgery and others were monitored, so it cannot prove which approach is best. Yet it offers a real-world look at how more than 7,000 Medicare patients with kidney tumors fared. Surgery is the standard treatment now.

"I think it should change care" and that older patients should be told "that they don't necessarily need to have the kidney tumor removed," said Dr. William Huang of New York University Langone Medical Center. "If the treatment doesn't improve cancer outcomes, then we should consider leaving them alone."

He led the study and will give results at a medical meeting in Orlando, Fla., later this week. The research was discussed Tuesday in a telephone news conference sponsored by the American Society of Clinical Oncology and two other cancer groups.

In the United States, about 65,000 new cases of kidney cancer and 13,700 deaths from the disease are expected this year. Two-thirds of cases are diagnosed at the local stage, when five-year survival is more than 90 percent.

However, most kidney tumors these days are found not because they cause symptoms, but are spotted by accident when people are having an X-ray or other imaging test for something else, like back trouble or chest pain.

Cancer experts increasingly question the need to treat certain slow-growing cancers that are not causing symptoms — prostate cancer in particular. Researchers wanted to know how life-threatening small kidney tumors were, especially in older people most likely to suffer complications from surgery.

They used federal cancer registries and Medicare records from 2000 to 2007 to find 8,317 people 66 and older with kidney tumors less than 1.5 inches wide.

Cancer was confirmed in 7,148 of them. About three-quarters of them had surgery and the rest chose to be monitored with periodic imaging tests.

After five years, 1,536 had died, including 191 of kidney cancer. For every 100 patients who chose monitoring, 11 more were alive at the five-year mark compared to the surgery group. Only 6 percent of those who chose monitoring eventually had surgery.

Furthermore, 27 percent of the surgery group but only 13 percent of the monitoring group developed a cardiovascular problem such as a heart attack, heart disease or stroke. These problems were more likely if doctors removed the entire kidney instead of just a part of it.

The results may help doctors persuade more patients to give monitoring a chance, said a cancer specialist with no role in the research, Dr. Bruce Roth of Washington University in St. Louis.

Some patients with any abnormality "can't sleep at night until something's done about it," he said. Doctors need to say, "We're not sticking our head in the sand, we're going to follow this" and can operate if it gets worse.

One of Huang's patients — 81-year-old Rhona Landorf, who lives in New York City — needed little persuasion.

"I was very happy not to have to be operated on," she said. "He said it's very slow growing and that having an operation would be worse for me than the cancer."

Landorf said her father had been a doctor, and she trusts her doctors' advice. Does she think about her tumor? "Not at all," she said.

___

Online:

Kidney cancer info: http://www.cancer.net/cancer-types/kidney-cancer

and http://www.cancer.gov/cancertopics/types/kidney

Study: http://gucasym.org

___

Marilynn Marchione can be followed at http://twitter.com/MMarchioneAP

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State of the Union: Obama Pushes Job Creation

Pursuing an aggressive and diverse early second-term agenda, President Obama turned his focus Tuesday night squarely to the economy, using his State of the Union address to unveil new government initiatives aimed at creating jobs.

The defining duty of the new Congress and new administration is to "reignite the true engine of America's economic growth -- a rising, thriving middle class," Obama said Tuesday night from the House chamber.

"That must be the North Star that guides our efforts," he said.

Obama's proposals had a familiar ring, including re-packaged economic ideas but also offering several bold new measures aimed at boosting the middle class.

None of the proposals would add to the deficit "by a single dime," Obama pledged, with costs offset by savings carved out in the budget and from money saved from ending two wars.

"It's not a bigger government we need, but a smarter government that sets priorities and invests in broad-based growth," Obama said.

For the first time as president, Obama called for raising the minimum wage from $7.25 to $9.00 an hour by 2015. He proposed to ensure future increases by indexing the minimum wage to inflation.

He proposed a national goal of universal pre-school education, an effort to help states provide tens of thousands of low- to middle-income four-year-old children access to quality public education from an earlier age.

Charles Dharapak/Pool/AP Photo

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And, to heal the nation's crumbling roads and bridges, Obama offered a $50 billion "fix it first" infrastructure program that would prioritize repair of existing structures before building new ones.

"Every day, we should ask ourselves three questions as a nation," Obama said. "How do we attract more jobs to our shores? How do we equip our people with the skills needed to do those jobs? And how do we make sure that hard work leads to a decent living?"

Answers to those questions, the president suggested, include redoubling investments in clean energy technologies -- a step which he said would both benefit the environment and reduce U.S. dependence on foreign oil.

"For the sake of our children and our future, we must do more to combat climate change," he said.

He called for doubling the amount of renewable electricity generation in the U.S. by 2020, and announced an energy version of his "Race to the Top" education program that would give states grants for the best energy efficiency programs.

Related: 7 Things Obama Says at Every State of the Union

In tandem with his economic focus, Obama announced the withdrawal of 34,000 U.S. troops from Afghanistan by this time next year, cutting in half the current force and marking a quickened pace for the final exit of U.S. combat forces by a 2014 deadline.

There are currently 66,000 U.S. troops serving in Afghanistan. Obama has vowed to bring nearly all of them home by the end of next year, though a small contingent will likely remain to train Afghan forces and assist counterterrorism operations, officials have said.

Obama touched briefly on his recently-unveiled proposals to overhaul the nation's immigration system, expand rights for gay and lesbian Americans and curb an epidemic of gun violence.

With dozens of victims of gun violence looking on from the House gallery, including former Rep. Gabby Giffords, and families of victims from shootings at Newtown, Conn., Oak Creek, Wisc., and Aurora, Colo., Obama made an emotional plea for an up-or-down vote on his gun control plan.

"Each of these proposals deserves a vote in Congress," he said of proposed restrictions on assault-style weapons and high capacity magazines, and enhanced background checks, among other measures.

"If you want to vote no, that's your choice," he said. "But these proposals deserve a vote. Because in the two months since Newtown, more than a thousand birthdays, graduations and anniversaries have been stolen from our lives by a bullet from a gun."

Read More: President Obama's Past State of the Union Promises

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Pope's sudden resignation sends shockwaves through Church

VATICAN CITY (Reuters) - Pope Benedict stunned the Roman Catholic Church on Monday when he announced he would stand down, the first pope to do so in 700 years, saying he no longer had the mental and physical strength to carry on.

Church officials tried to relay a climate of calm confidence in the running of a 2,000-year-old institution, but the decision could lead to uncertainty in a Church already besieged by scandal for covering up sexual abuse of children by priests.

The soft-spoken German, who always maintained that he never wanted to be pope, was an uncompromising conservative on social and theological issues, fighting what he regarded as the increasing secularization of society.

It remains to be seen whether his successor will continue such battles or do more to bend with the times.

Despite his firm opposition to tolerance of homosexual acts, his eight year reign saw gay marriage accepted in many countries. He has staunchly resisted allowing women to be ordained as priests, and opposed embryonic stem cell research, although he retreated slightly from the position that condoms could never be used to fight AIDS.

He repeatedly apologized for the Church's failure to root out child abuse by priests, but critics said he did too little and the efforts failed to stop a rapid decline in Church attendance in the West, especially in his native Europe.

In addition to child sexual abuse crises, his papacy saw the Church rocked by Muslim anger after he compared Islam to violence. Jews were upset over rehabilitation of a Holocaust denier. During a scandal over the Church's business dealings, his butler was accused of leaking his private papers.

In an announcement read to cardinals in Latin, the universal language of the Church, the 85-year-old said: "Well aware of the seriousness of this act, with full freedom I declare that I renounce the ministry of Bishop of Rome, Successor of St Peter ...

"As from 28 February 2013, at 20:00 hours (1900 GMT) the See of Rome, the See of St. Peter will be vacant and a conclave to elect the new Supreme Pontiff will have to be convoked by those whose competence it is."

POPE DOESN'T FEAR SCHISM

Benedict is expected to go into isolation for at least a while after his resignation. Vatican spokesman Father Federico Lombardi said Benedict did not intend to influence the decision of the cardinals in a secret conclave to elect a successor.

A new leader of the world's 1.2 billion Roman Catholics could be elected as soon as Palm Sunday, on March 24, and be ready to take over by Easter a week later, Lombardi said.

Several popes in the past, including Benedict's predecessor John Paul, have refrained from stepping down over their health, because of the division that could be caused by having an "ex-pope" and a reigning pope alive at the same time.

Lombardi said the pope did not fear a possible "schism", with Catholics owing allegiances to a past and present pope in case of differences on Church teachings.

He indicated the complex machinery of the process to elect a new pope would move quickly because the Vatican would not have to wait until after the elaborate funeral services for a pope.

It is not clear if Benedict will have a public life after he resigns. Lombardi said Benedict would first go to the papal summer residence south of Rome and then move into a cloistered convent inside the Vatican walls.

The resignation means that cardinals from around the world will begin arriving in Rome in March and after preliminary meetings, lock themselves in a secret conclave and elect the new pope from among themselves in votes in the Sistine Chapel.

There has been growing pressure on the Church for it to choose a pope from the developing world to better reflect where most Catholics live and where the Church is growing.

"It could be time for a black pope, or a yellow one, or a red one, or a Latin American," said Guatemala's Archbishop Oscar Julio Vian Morales.

The cardinals may also want a younger man. John Paul was 58 when he was elected in 1978. Benedict was 20 years older.

"We have had two intellectuals in a row, two academics, perhaps it is time for a diplomat," said Father Tom Reese, senior fellow at the Woodstock Theological Center at Georgetown University. "Rather than electing the smartest man in the room, they should elect the man who will listen to all the other smart people in the Church."

Liberals have already begun calling for a pope that would be more open to reform.

"The current system remains an 'old boy's club' and does not allow for women's voices to participate in the decision of the next leader of our Church," said the Women's Ordination Conference, a group that wants women to be able to be priests.

"GREAT COURAGE"

The last pope to resign willingly was Celestine V in 1294 after reigning for only five months, his resignation was known as "the great refusal" and was condemned by the poet Dante in the "Divine Comedy". Gregory XII reluctantly abdicated in 1415 to end a dispute with a rival claimant to the papacy.

Lombardi said Benedict's stepping aside showed "great courage". He ruled out any specific illness or depression and said the decision was made in the last few months "without outside pressure". But the decision was not without controversy.

"This is disconcerting, he is leaving his flock," said Alessandra Mussolini, a parliamentarian who is granddaughter of Italy's wartime dictator. "The pope is not any man. He is the vicar of Christ. He should stay on to the end, go ahead and bear his cross to the end. This is a huge sign of world destabilization that will weaken the Church."

Cardinal Stanislaw Dziwisz, secretary to the late Pope John Paul, said the former pope had stayed on despite failing health for the last decade of his life as he believed "you cannot come down from the cross."

While the pope had slowed down recently - he started using a cane and a wheeled platform to take him up the long aisle in St Peter's Square - he had given no hint recently that he was considering such a dramatic decision.

Elected in 2005 to succeed the enormously popular John Paul, Benedict never appeared to feel comfortable in the job.

"MIND AND BODY"

In his announcement, the pope told the cardinals that in order to govern "... both strength of mind and body are necessary, strength which in the last few months, has deteriorated in me to the extent that I have had to recognize my incapacity to adequately fulfill the ministry entrusted to me."

Before he was elected pope, the former Cardinal Joseph Ratzinger was known as "God's rottweiler" for his stern stand on theological issues. After a few months, he showed a milder side but he never drew the kind of adulation that had marked the 27-year papacy of his predecessor John Paul.

U.S. President Barack Obama extended prayers to Benedict and best wishes to those who would choose his successor.

German Chancellor Angela Merkel said the pope's decision must be respected if he feels he is too weak to carry out his duties. British Prime Minister David Cameron said: "He will be missed as a spiritual leader to millions."

The Archbishop of Canterbury, leader of the worldwide Anglican communion, said he had learned of the pope's decision with a heavy heart but complete understanding.

CHEERS AND SCANDAL

Elected to the papacy on April 19, 2005, Benedict ruled over a slower-paced, more cerebral and less impulsive Vatican.

But while conservatives cheered him for trying to reaffirm traditional Catholic identity, his critics accused him of turning back the clock on reforms by nearly half a century and hurting dialogue with Muslims, Jews and other Christians.

After appearing uncomfortable in the limelight at the start, he began feeling at home with his new job and showed that he intended to be pope in his way.

Despite great reverence for his charismatic, globe-trotting predecessor -- whom he put on the fast track to sainthood and whom he beatified in 2011 -- aides said he was determined not to change his quiet manner to imitate John Paul's style.

A quiet, professorial type who relaxed by playing the piano, he showed the gentle side of a man who was the Vatican's chief doctrinal enforcer for nearly a quarter of a century.

The first German pope for some 1,000 years and the second non-Italian in a row, he traveled regularly, making about four foreign trips a year, but never managed to draw the oceanic crowds of his predecessor.

The child abuse scandals hounded most of his papacy. He ordered an official inquiry into abuse in Ireland, which led to the resignation of several bishops.

Scandal from a source much closer to home hit in 2012 when the pontiff's butler, responsible for dressing him and bringing him meals, was found to be the source of leaked documents alleging corruption in the Vatican's business dealings.

Benedict confronted his own country's past when he visited the Nazi death camp at Auschwitz. Calling himself "a son of Germany", he prayed and asked why God was silent when 1.5 million victims, most of them Jews, were killed there.

Ratzinger served in the Hitler Youth during World War Two when membership was compulsory. He was never a member of the Nazi party and his family opposed Adolf Hitler's regime.

(Additional reporting by James Mackenzie, Barry Moody, Cristiano Corvino, Alexandra Hudson in Berlin, and Dagamara Leszkowixa in Poland; Editing by Peter Graff)

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Benedict's resignation renews calls for an African pope

LAGOS: Pope Benedict XVI's resignation has sparked calls for his successor to come from Africa, home to the world's fastest-growing population and the front line of key issues facing the Roman Catholic Church.

Around 15 per cent of the world's 1.2 billion Catholics live in Africa and the percentage has expanded significantly in recent years in comparison to other parts of the world.

Much of the Catholic Church's recent growth has come in the developing world, with the most rapid expansions in Africa and Southeast Asia.

Names such as Ghana's Peter Turkson and Nigerian John Onaiyekan have been mentioned as potential papal material, as has Francis Arinze, also from Nigeria and considered a possibility when Benedict was elected, but who is now 80.

Some analysts see the issue as one of justice since Africa has contributed to the Catholic Church to such a large degree, as well as a reflection of a changing world.

"I think that, with the black community's representation in the larger Catholic community, it is legitimate that we have a black pope," said Rene Legre Hokou, head of the Ivory Coast League of Human Rights.

"An African pope could give more vitality to the Catholic Church in the black world. It would demonstrate the universal character of the religion."

A number of African Catholic Church members had a mixed view however, saying they would like to see a fellow African elected pope, but wanted the most qualified person, no matter where he is from.

Pat Utomi, a prominent Catholic in Nigeria who is an economist and former presidential candidate, said he would take pride in seeing an African elected, "but we must take that away."

"I think what matters is the right person with the vision for the moment," Utomi said.

At the same time, he said Africa in several ways was representative of major challenges facing the Church, particularly its relationship with an evangelical movement with explosive growth on the continent as well as with Islam.

"I think in some ways a John Paul II was a response to the Soviet Union," Utomi said. "In some ways the challenge of the Church must be to reach an accommodation ... an understanding with Islam and the Pentecostal movement."

Africans have flocked to evangelical religions, with many seeing them as more relevant to their daily lives, posing a challenge to the Catholic Church.

Also in countries like Nigeria, roughly divided between a mainly Muslim north and predominately Christian south, religious and ethnic tensions have led to violence.

Onaiyekan, nominated as a cardinal in October and also the archbishop of the Nigerian capital Abuja, has made efforts to foster unity between Christians and Muslims in his country.

"It would take a skilled leader of the church -- in the kind of way that a John Paul II reached out to the Eastern church, to the Orthodox churches of the east," Utomi said.

Vatican watchers say the college of cardinals may seize the moment to elect a Latin-American, African or Asian pope.

Others say 85-year-old Benedict -- who is resigning for age reasons -- may call on the cardinals to elect someone younger, who is less likely to suffer failing health early in his mandate.

Benedict visited Africa twice, most recently the West African nation of Benin in 2011, while before that Angola and Cameroon in 2009. His Benin visit came 150 years after what is considered the evangelisation of the country by missionaries.

Archbishop of Lagos Alfred Adewale Martins said Benedict should be lauded for his efforts in Africa.

"I believe he is one man that we should be grateful to God for the attitude to the church in general and also the solicitude that he has demonstrated in very many ways to the church in Africa in particular," said Martins.

But Benedict's outreach on the continent notwithstanding, there were still doubts over whether an African would be put at the head of the Vatican.

At Saint Antonio da Polana Church in the Mozambique capital Maputo after Benedict's announcement, parishioner Zeb Renardo said he did not think the time had come.

"I will say categorically that I doubt we will have an African pope," he said. "I think the moment hasn't come for us to see an African pope."

But the rector at Ivory Coast's Basilica of Our Lady of Peace of Yamoussoukro, a semi-replica of St. Peter's in Rome and the largest Christian shrine in Africa, said "why not a non-Western pope?"

"The world is now multi-colour," Polish priest Stanislaw Skuza said.

- AFP/ck

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Afzal Guru hanging: Fourth day of curfew in tension torn Kashmir

SRINAGAR: Uninterrupted curfew restrictions continued for the fourth day on Tuesday in Kashmir Valley to prevent violence in the wake of Afzal Guru's hanging in New Delhi's Tihar jail. Chief Minister Omar Abdullah said he would help arrange a visit to the parliament attack convict's family to offer prayers at his grave.

While speaking to a radio channel on Monday evening, Omar said that if Afzal Guru's family approached him, he would do everything possible to help.

Three people have died so far during protests in the Kashmir Valley after news of December 2001 Parliament attack plotter's hanging spread in Srinagar.

Residents in Batwina village of north Kashmir's Ganderbal district said two youths were drowned after they were chased by the security forces during protests, while police said the deaths had occurred because of a boat capsize in the Jhelum river.

A teenaged boy belonging to Watergam (Rafiabad) area of Baramulla district succumbed to critical injuries in a city hospital on Monday morning.

He had reportedly sustained a bullet injury from the security forces during protests in the village.

Another injured youth is battling for life in Srinagar's super specialty Sher-e-Kashmir Institute of Medical Sciences Soura.

The state government has ordered a magisterial probe into both these incidents and an ex-gratia relief to the next of kin of the deceased person.

Strict orders has been given to exercise maximum restraint while handling the law and order situation in the valley, the chief minister said.

Reports indicate 14 companies of border security force (BSF) and 10 additional companies of central reserve police force (CRPF) have been rushed to assist the state administration in maintaining law and order.

For the third day on Tuesday Kashmir went without any print editions of the local newspapers.

Local editors said they had been unofficially told by the authorities to suspend publications of their newspapers till Friday.

"If this has been done to check the spread of wild rumours then it is a very bad decision," said Bashir Manzar, editor of daily 'Kashmir Images'.

Cable television operations and Internet facilities also remained shut in the summer capital Srinagar, although BSNL broadband users said their facility was still working.

Those using dongle appliances and mobile phones to access the Internet have been unable to do so for the last four days.

A senior police officer said curfew imposed on Saturday would remain in place till further orders.

Asked whether the authorities were planning some relaxation in the imposed curfew, the officer said the situation was being monitored on a regular basis.

Authorities have made announcements through the local radio and television broadcasts that additional round-the-clock ambulances have been made available to ferry sick people to hospitals from areas under curfew.

Security forces have been advised to treat the identity cards of those maintaining essential services like healthcare, water supplies and electricity as curfew passes and allow their movements through those areas.

Separatist Hurriyat group headed by Syed Ali Geelani has asked people to continue the protest shutdown till Friday when a march to the Eidgah grounds has been announced.

"We will demand that the mortal remains of Afzal Guru be returned to his family," a spokesman of the group told media here.

All examinations and interviews scheduled to be held up to Februay 17 have been postponed by the authorities.

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